Mucosal Lymphoid Infiltrate Dominates Colonic Pathological Changes in Murine Experimental Shigellosis
نویسندگان
چکیده
منابع مشابه
Studies on Experimental Shigellosis
Host resistance to Shigella infections can be decreased by non-specific physical stress. Fasting lowers the number of Shigella required for a parenteral LD(50) dose. While the LD(50) by the oral route is larger in fasted than in nonfasted animals, the fasted host's susceptibility to oral infection is increased as evidenced by the increased fecal Shigella carrier state, duration of intestinal in...
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The gram-negative pathogen Shigella flexneri causes bacillary dysentery, an invasive disease of the human colonic mucosa. A major characteristic of the infectious process is the occurrence of an acute inflammatory reaction of mucosal tissues which is generally consequence of primary invasion and destruction of colonic epithelial cells by the pathogen. Confirming in vitro demonstration that S. f...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2005
ISSN: 0022-1899,1537-6613
DOI: 10.1086/430740